The ICSPIS 2021 is focusing on the important impact of signal processing and information security on the advances in technologies. The conference is an excellent forum for researchers from all over the world to submit papers of their research in the following topics. Sessions will include video presentations on new research findings. Papers describing original work are invited in any of the areas listed below. Accepted papers will be published in the Proceedings of ICSPIS 2021 and will be submitted for possible inclusion to the IEEE Xplore® digital library. Acceptance will be based on quality, relevance, and originality.